Current Treatment

Literature Library

For more information on rosacea research, access our literature library below.

To view the complete articles about rosacea, click here to access Pubmed.org, where these article citations can be found and purchased.

Buechner S A. Rosacea: an update. Dermatology. 2005;210:100-108.

Abstract
Rosacea is a common chronic cutaneous disorder of unknown etiology which occurs most commonly in middle-aged individuals. Cutaneous manifestations include transient or persistent facial erythema, telangiectasia, edema, papules and pustules that are usually confined to the central portion of the face. The National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea identified four subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous and ocular. Recently, a standard grading system for assessing gradations of the severity of rosacea has been reported. Little is known about the cause of rosacea. Genetic, environmental, vascular, inflammatory factors and microorganisms such as Demodex folliculorum and Helicobacter pylori have been considered. Topical metronidazole and azelaic acid have been demonstrated to be effective treatments for rosacea. Severer or persistent cases may be treated with oral metronidazole, tetracyclines or isotretinoin.

Millikan L. The proposed inflammatory pathophysiology of rosacea: implications for treatment. SKINmed: Dermatology for the Clinician. 2003;2(1):43-47.

Abstract
The pathophysiology of the vascular and inflammatory stages of facial rosacea and proposes an underlying cause is reviewed. It can be argued that all the stigmata of rosacea are manifestations of an inflammatory process: neutrophilic dermatosis. For this reason, treatments that block neutrophil involvement in the development of rosacea, such as topical metronidazole and systemic antibodies, should be considered first-line therapy for all stages of the disease.

Jansen T, Plewig G, Rosacea: classification and treatment. J R Soc Med. 1997;90(3):144-150.

Abstract
None Available

Wilkin J, Dahl M, Detmar M, Drake L, Feinstein A, Odom R, et al. Standard classification of rosacea: report of the National Rosacea Society Expert Committee on the classification and staging of rosacea. J Am Acad Dermatol. 2002;46(4):584-587.

Abstract
None Available

Wilkin J, Dahl M, Detmar M, Drake L, Liang R, Odom R, et al. Standard grading system for rosacea: report of the National Rosacea Society Expert Committee on the classification and staging of rosacea*1, *2. J Am Acad Dermatol. 2004;50(6):907-912

Abstract
None Available

To view the above articles about rosacea, click here to access Pubmed.org, where these article citations can be found and purchased.